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Early impairment of NGF/TrkA signaling in AD can lead to reduced synaptic vesicle secretion and decreased presynaptic protein expression, resulting in presynaptic functional impairment of cholinergic primary neurons [88]

Upon release into the environment, they undergo a complex physicochemical transformation into more recalcitrant and even more toxic products

After overnight incubation, 0.1 ml of a dodecyl sulfate solution (10%) containing HCl (10 mM) was added to the wells

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