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Indocyanine green (ICG) is the only NIR fluorescent agent currently approved for human use

However, the cartilage tissue generated from FOXO4-DRI pretreated PDL9 cells displayed lower expression of senescence-relevant secretory factors than that from the untreated control group

Systemic causes Diabetes Obesity Hypothyroidism Pregnancy Menopause Systemic lupus erythematosus Scleroderma Dermatomyositis Renal failure Long-term hemodialysis Acromegaly Multiple myeloma Sarcoidosis Leukaemia Alcoholism Haemophilia PATHOPHYSIOLOGY The most popular ones are mechanical compression, micro-vascular insufficiency, and vibration theories

The deep blue color comes from the copper itself it is a sign of concentration, not a dye

Bourdeau, 2009