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These results suggest that NAC prevents retinal degeneration in EAAC1 KO mice, but not in GLAST KO mice, at least partly by increasing the GSH levels and suppressing the oxidative stress levels in the retina

10.1124/jpet.102.053124 J

Smith RG, et al

Therefore, critically analyzing negative clinical results is necessary to avoid misleading conclusions, standardize the clinical relevance of endpoint indicators, and promote the rational development of the antiaging field

Enabling fully automated analysis, thrombus length is calculated using the maximum Feret diameter (greatest distance between the two parallel planes) and thrombus width is derived from its orthogonal dimension