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It was first isolated from the cerebral venous blood of rabbits in 1977 by Schoenenberger and Monnier, following electrical stimulation of the thalamus during sleep induction experiments giving rise to its name

Semaglutide Study Finds Link to Blood Clots A 2021 study published in the Endocrine Journal (Volume 68, Issue 6, pages 739-742) found that type 2 diabetes patients using semaglutide were at a 266% increased risk of deep vein thrombosis

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It activates genes associated with health and vitality while suppressing genes associated with aging and inflammation

[1] [2] The most commonly reported adverse effects of semaglutide are gastrointestinal in nature, reflecting its mechanism of action on the digestive system