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3.4 Smokers and non-smokers perceptions of the six packs Among the six mock-up cigarette packs, both non-smokers and smokers ranked Pack 1 as the most visually appealing pack overall, the pack with the highest quality cigarettes, the most harmful to health, simultaneously the easiest and hardest to quit with, and the pack they would not smoke

Chronic exposure to this smoke causes metaplastic alterations to the respiratory mucosa with an increase in the number and size of goblet cells and consequent increase in upper airway secretion.17,18 Cohen et al.13 and Kreindler et al.19 also showed in vitro that exposure to cigarette smoke inhibits chloride transport in epithelial cells, causing physiological alterations similar to those found in patients with cystic fibrosis

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