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MS/MS parameters were optimized by injecting 10 L of 10 ng/mL individual standard solutions in acetonitrile

During Period B, flare of HS, defined as 25% increase from baseline in abscesses and inflammatory nodule counts and with a minimum of 2 additional lesions, was documented in 22 (22%) of the 100 subjects who were withdrawn from HUMIRA treatment following the primary efficacy timepoint in two studies

10.1038/nm.2736 [DOI] [PMC free article] [PubMed] [Google Scholar] Jin S