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Using bronchial epithelial cells and human lung organoids, we demonstrate that chronic WCSE exposure induces a coordinated redoxmitochondrial adaptation, supporting survival under persistent oxidative stress

Pain Quality: Heartburn and acid reflux typically produce a burning or discomforting sensation, whereas a heart attack is characterized by intense pressure or squeezing in the chest

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Maternal smoking and its association with birth weight

This is consistent with reports that GSK3 promotes NRF2 degradation, whereas AKT-mediated phosphorylation of GSK3 inhibits this process, thereby stabilizing NRF2 and enhancing its nuclear localization 11,20,26,28