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Upon ceasing use, nicotine is broken down by the liver into several byproducts, primarily cotinine

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Effect of Nicotinic Acetylcholine Receptor Alpha7 Subunit Gene on Liver Inflammatory Reaction in Mice With Nonalcoholic Steatohepatitis and Related Mechanisms

2013;132:95-100.[PubMed Abstract] - 14.Ward Z, Platt L, Sweeney S, et al

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