CS-induced EVs as biomarkers for the diagnosis and treatment of diseases The exposure of CS could increase the production of EVs from diverse types of cells, including endothelial cells, epithelial cells and fibroblasts, which might rely on the redox modifications of protein thiols [45, 46]
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In 1989, Philip Morris entered the fray with a virtually nicotine-free cigarette called Next that it claimed was better than other low-nicotine varieties because its taste was indistinguishable from regular cigarettes