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Online supplemental appendix table A2 shows the predicted percent reductions in cigarette consumption if all countries had increased their scores from 0 in 2014 to 5 in 2020

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Given the centrality therefore of nicotine delivery and subjective effects in determining the THR potential of non-combustible tobacco products including HTPs, this paper reports a clinical study designed to assess nicotine pharmacokinetics and various subjective effects measures in adult smokers when they used three different variants of iD tobacco sticks with the Pulze HTS