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a 1995 study found that high-dose transdermal nicotine was safe and effective for heavy smokers [35, 36]

Yuki D, Takeshige Y, Nakaya K, Futamura Y (2018) Assessment of the exposure to harmful and potentially harmful constituents in healthy Japanese smokers using a novel tobacco vapor product compared with conventional cigarettes and smoking abstinence

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The illegal factory, investigators say, was capable of generating an illicit profit of 350,000 euros per day , exceeding 120 million euros per year, causing an estimated loss to public finances of around 80 million euros

Neurobiological research on N,N-dimethyltryptamine (DMT) and its potentiation by monoamine oxidase (MAO) inhibition: from ayahuasca to synthetic combinations of DMT and MAO inhibitors