Considering the rate of MVP observed in our cEDS cohort and the knowledge that the mitral valve depends upon collagen for its tensile strength and that myxomatous MVP is characterized by disruption of the collagen layer with expansion of glycosaminoglycans within the middle layer of the valve [123], it is reasonable to consider MVP as a potential clue for cEDS, although the true clinical significance is so far unknown
Newly transplanted grafts need oxygen and nutrients to survive in their new location
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This is because, at high oscillation frequencies (20 Hz), the signal is dominated by the characteristics of the upper airways, whereas at low frequencies (below 10 Hz), the signal reflects the entire tracheobronchial tree, including small airway resistance
surgeon general, the World Health Organization and the Centers for Disease Control and Prevention have all concluded that raising taxes helps large numbers of smokers to quit and have advocated loudly for it
