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The effect of liquid application on global gene expression, stress-responsive signaling protein phosphorylation, growth factor secretion, pro-inflammatory cytokine secretion, trans-epithelial electrical resistance (TEER), and permeability to a 20 kDa fluorescent dextran was then determined immediately after 6 and 24 h of liquid application (Figure 1A)

2 Consider REDUCE TO QUIT for patients who: Want to reduce smoking before quitting on a target quit date (TQD) Want to reduce their smoking, but not set a TQD Trying a reduction strategy is better than doing nothing at all