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Participants who quit smoking had significantly greater reductions in V S /f P across regions than non-quitters, and correlations were found between reductions in cigarettes per day and decreases in V S /f P for brainstem and cerebellum, but there was no between-group effect of treatment type
These genetic differences explain why only 10-20% of smokers never become addicted despite nicotine exposure, highlighting the biological basis of addiction vulnerability
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Consequently, second and thirdhand smoke may lead to a significant unnoticed uptake of NNK
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