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95% CI, 1.613.6) was found to be the strongest predictor of these skin lesions, hence one might extrapolate that ustekinumab could be a preferred biologic option in current smokers as at least in a subset of patients, smoking may promote inflammatory pathways amenable to ustekinumabs anti-IL-12/IL-23 activity, though this obviously requires further confirmation both from a mechanistic and clinical perspective [29]
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Surgeon General Everett Koop issued a 1982 report showing that 30 percent of all cancer deaths were attributable to smoking, and used his bully pulpit to inveigh against the hazards of secondhand smoke
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She has public artwork at PS 92Q, Queens NY, and HHS Lerner Children Pavilion, New York, NY
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