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agencies issued guidance and cautionary statements about the increased risk posed by COVID-19 to smokers: Those who smoke cigarettes may be at increased risk from COVID-19 infection and may have worse outcomes from COVID-19, the U.S

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Respiratory sensitization: besides local lung inflammation, respiratory sensitization is yet another toxicological endpoint that is currently not given much attention in e-cigarette research, despite reported cases of allergic reactions occurring in the lungs after e-cigarette use (Azevedo et al