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Studies of smokers cutting down while using NRT have found that while blood nicotine levels generally remain stable or slightly higher, carbon monoxide readings decreased

Masoudi Soltani, S., Kazemi Yazdi, S., Hosseini, S

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Additionally, when adjusted for confounding factors, the odds of hyperuricemia increased as smoking duration, smoking intensity, and cumulative dose increased in females (all p for trend 0.004)