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In addition to the direct cytotoxic and genotoxic effects on epithelial cells, cannabis smoking alters lung immune homeostasis, leading to an inflammatory response and functional impairment of alveolar macrophages (AMs), which play a critical role in airway surveillance and pathogen clearance

[DOI] [PMC free article] [PubMed] [Google Scholar] 204.Hill W., Lim E.L., Weeden C.E., Lee C., Augustine M., Chen K., Kuan F.-C., Marongiu F., Evans E.J., Moore D.A., et al

This means smoking (and potentially vaping, depending on company policy) is prohibited in vehicles used for work, such as company cars, taxis, and limousines