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Zyn nicotine pouches can lead to mouth ulcers due to mechanical friction and chemical irritation from nicotine, flavorings, and pouch materials

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Research shows it may help manage high blood pressure by relaxing the blood vessels that get tight and stiff from smoking

The challenges encountered to date with the implementation of this investigator-initiated study have been primarily related to the lack of ready access to matching placebo patches that satisfy the safety and manufacturing requirements of clinical trial regulators in Canada

Expect MOQs of 1-10 sets and prices from $8,000 to $250,000