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However, smoking negatively impacts arterial health by reducing their ability to contract normally and causing blockages, thus obstructing blood flow

On the contrary, PAD expression and activity are increased in the lungs of smokers [29] the explanation for this might be that PAD is originally located intracellularly, and citrullinated proteins may be released into the extracellular matrix after apoptosis

6 Nicotine is addictive and is unsafe for young people and pregnant women

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