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Additionally, two sensitivity analyses were conducted: one assessing the impact of including only studies with objective COPD diagnoses (e.g., spirometry) while excluding self-reported cases, and another including only studies with a NOS score 7 to evaluate the effect of study quality on the results

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Medication Certain medications can cause acid reflux, including iron supplements, over-the-counter medications (aspirin and ibuprofen), antibiotics, and some prescription medications for asthma, emphysema, high blood pressure, anxiety, and osteoporosis

doi:10.1136/bmjopen-2020-042623 39

Amaker 1988, pp