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Biologics targeting the IL-4R, IL-5/IL-5R, IL-33/ST2, and TSLP pathways have emerged as promising interventions to reduce exacerbations and improve lung function, demonstrating clear efficacy in patients with eosinophilic or type 2-high signatures

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PMI's own in vivo clinical data on biomarkers of potential harm in Americans show that IQOS is not detectably different from conventional cigarettes

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Of the 1,500 smokers surveyed by Censuswide, over a third (36%) mistakenly think cigarette butts contain cotton wool when in fact the white fluffy material is made from a type of plastic (cellulose acetate) which once smoked, can release thousands of chemicals