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The Science Consortium and its members have also donated millions of dollars to advancing animal-free toxicity testing approaches through equipment donations, travel awards, research grants, and training opportunities

Thus, over the decades, despite millions of smokers smoking fewer sticks or quitting altogether, the demand from those who keep the habit has led to not just more revenue for Altria but more revenue at higher margins

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10.1016/s0303-7207(01)00624-4 38

Sources: Data used to create this ranking were collected as of December 17, 2025 from the U.S