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doi: 10.1523/ENEURO.0279-20.2020 61

By then the company was already the target of multiple investigations and lawsuits by federal, state and local officials as well as class action attorneys

The fact that THC binds with important cannabinoid receptors in the brain, and the fact that THC can pass from the mother through the placenta to the developing fetus indeed raises questions about the safety of exposing an unborn baby to THC

Moreover, the role of regulatory environments is evident in regional comparisons across Southeast Asia, where adolescent e-cigarette use is lowest in Thailand (3.36.7%), where strict bans are in place, and highest in Indonesia (10.711.8%), where legal sales are permitted although heavily taxed [45, 46]

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