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Conclusions Collectively, these findings emphasize brain regions (e.g., ventromedial PFC, insula, thalamus) critically linked with cigarette smoking, suggest neuroimaging paradigms warranting additional consideration among smokers (e.g., pain processing), and highlight regions in need of further elucidation in addiction (e.g., cerebellum)

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Reynolds Tobacco Company was founded in 1875 and produced chewing tobacco, exclusively) cigarettes were slowly taking sway

Taylor, R., Najafi, F