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(2019) E-Cigarettes for Smoking Cessation A randomized clinical trial published in the New England Journal of Medicine (PMID: 30699054) found that e-cigarettes were nearly twice as effective as nicotine replacement therapy (NRT) for smoking cessation

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Our study results in mice were not meant to be compared to human disease, but instead argue that e-cigarette smoke must be more thoroughly studied before it is deemed safe or marketed that way. Nicotine and Nitrosamines The question of whether nicotine itself, separate from tobacco smoke, causes cancer is controversial because of conflicting study results over time that used oft-criticized methods

The sale of cigarettes without necessary stamps is therefore considered illicit and opens criminal persecution against the individuals behind the sale and processing of such cigarettes