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Less than 40% of smokers used treatment like counseling or medication, and only half received advice or help from a healthcare provider to quit, as reported by the Centers for Disease Control and Prevention titled Adult Smoking Cessation United States, 2022. In contrast, structured therapies, including behavioral therapy and nicotine replacement therapy (NRT), significantly increase the likelihood of successfully quitting

Briefly, the studies that were extracted represented several types of study design (for example, cohort and casecontrol studies), measured exposure in several different ways and varied in their choice of reference categories (where some compared current smokers with never smokers, whereas others compared current smokers with nonsmokers or former smokers)