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A range of approaches have been used by others, from using the exposure prevalence of control subjects in casecontrol studies (IARC, 2007) to extrapolation from exposure of children to ETS at home (Jamrozik, 2005)

However, as evident between 1999 and 2002, 2011 and 2014, and 2017 and 2022/2023, as the size of the leading RYO pouch decreased, the affordability of RYO tobacco either increased, or the decline in affordability decelerated

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