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In a statement, Imperial which employs 35,000 people in 160 countries, said it was undertaking "a number of restructuring projects to strengthen the group's competitive position." It said the measures, including the two factory closures, would be implemented over the next two years

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But differences were nonetheless apparent

When smoking duration was used as a continuous measure in place of cigarette pack years in the 3-category age of initiation model (Supplemental Table S3a in the online supplement), the association between childhood smoking and COPD was attenuated (aRR from 1.27 [95% CI=1.06, 1.51] to 1.16 [95% CI=0.99, 1.36])

That's why Tabac Info Service does not formally discourage it but advises discussing it with a competent healthcare professional beforehand