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The Health ministry listed a number of reasons to justify the ban on e-cigarettes These included: Threat to countrys tobacco control efforts Hindrance in achieving targets envisaged under Sustainable Development Goals, National Monitoring Framework for Prevention and Control of non-communicable diseases and National Health Policy, 2017 Overall interest of public health of the youth and pregnant women as well Addictive nature of nicotine Scant scientific evidence for use of e-cigarettes as effective tobacco cessation aids Safety concern of flavours in combination with nicotine The government also cited Article 47 of the Indian Constitution to justify the ban on e-cigarettes

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Conclusions In this review, we summarize the recent findings about the function of extracellular vesicles in the pathogenesis of cigarette smoke-induced diseases, and to infer their potential utilizations as diagnostic biomarkers, prognostic evaluation, and therapeutic targets of OLK in the future