In a 1971 paper, Dr Michael Russell, a psychiatrist at the Addiction Research Unit based at the Maudsley Hospital in south London, concluded that nicotine was the motivating force underlying smoking behaviour.[27] Then, in a 1976 British Medical Journal paper on low-tar cigarettes, Dr Russell acknowledged that simply asking people to stop smoking or smoke fewer cigarettes would not work.[28] Neither would reducing nicotine levels below the satisfaction levels for smokers
Immunobiology 214:761777 Cuzick J, Otto F, Baron JA, Brown PH, Burn J, Greenwald P, Jankowski J, La Vecchia C, Meyskens F, Senn HJ, Thun M (2009) Aspirin and non-steroidal anti-inflammatory drugs for cancer prevention: an international consensus statement
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