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Studies found that smoking greatly increases your risk of developing Buergers disease Buergers disease symptoms may include: Pale, red, or bluish fingers or toes Tissue damage or gangrene (tissue decay) Painful sores on the fingers or toes In addition, you may feel coldness in your hands or feet and/or experience pain in any of those body parts

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= 0.40) and was in strong LD with the top eQTL for REV3L in cerebellum ( r 2 = 0.86 with rs9487668 in 1000 Genomes Europeans)