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While higher prices may deter some youth from using e-cigarettes, given the apparently large current appetite for black-market vapes that the EVALI epidemic revealed, coupled with the evidence from tobacco taxes and ITTP, it seems very likely that high taxes on e-cigarettes will drive more youth demand toward less reputable and potentially much more dangerous sources

Since few US states and localities have successfully implemented POS advertising restrictions, their impact in the US is not well known, but they are expected to reverse some of the effects of advertising, such as reducing youth uptake, reducing tobacco-related disparities, and changing norms about tobacco use

The systematic reviews that we included did not provide data on all populations who may be disproportionately affected and did not address cultural considerations in tobacco use and cessation

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