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(For a description of transplacental genotoxic effects in rodents, see the section on Genotoxicity earlier in this chapter.) Developmental effects from exposure to cigarette smoke were further studied in the curly-tail mouse and in the C57BL strain, a strain not predisposed to neural tube defects (Seller and Bnait 1995)

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Your brain adapts to a daily dose, and pulling that dose away overnight forces a system that has rebalanced around the medication to lurch back with no warning