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In contrast, enhanced cough to capsaicin stimulation was not observed until guinea-pigs had been exposed to TS for 4 days, but thereafter cough sensitivity also remained elevated for 10 days

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A single cigarette contains thousands of chemicals, including nicotine, aldehydes, and heavy metals like cadmium and lead

Strengths of the analysis include the use of well-validated and representative population data over many years, and extensive sensitivity testing to establish the robustness of the model and findings across a range of assumptions, including different specifications of the cut-off year for the beginning of the e-cigarette era

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