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There's a limit as to how much the lungs will take." In fact, a study led by Donny and funded by the National Institute on Drug Abuse and the FDA found that smokers randomly assigned to smoke low-nicotine cigarettes actually smoked fewer of the cigarettes in the sixth and final week than those assigned to smoke cigarettes with the conventional amount of nicotine

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Furthermore, out of these 20 studies, 12 had been funded by the tobacco industry itself

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It can also be caused by high blood pressure, obesity, or chronic kidney disease