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Mechanistically, this focal accumulation is thought to result from the synergistic effects of cytokines such as IL-4, IL-33, and TSLP, along with chemokines such as CCL17 and CCL22 within the inflamed tissue microenvironment (65, 66)

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While e-cigarettes dont contain the carcinogens that come from burning tobacco, the vapor does contain highly addictive nicotine as well as other chemicals whose health risks we are only beginning to understand