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In severe cases, this dysregulation resembles what psychologists refer to as social jet lag, where internal timing is constantly out of sync with the environment

PMID: 37195268 Messaging on mortality effects of VLNC cigarettes (i.e., cigarettes with 95% less nicotine are as deadly as current cigarettes) was associated with more accurate perceptions of the health risks of VLNC cigarettes than the control

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These conditions may impair cardiovascular reserve and limit compensatory responses to hemodynamic stress, ultimately leading to increased pulmonary artery pressures and pulmonary edema [28]

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