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In very rare individuals, especially (but not exclusively) in those with the COL1A1 p.(Arg312Cys) missense variant, spontaneous rupture of large arteries, intracranial aneurysms, and arteriovenous fistulae may occur [5,6,7, 9,10,11,12,13,14, 18,19,20,21,22,23,24,25,26]

After shifting stories or swapping out segment ideas, the show is usually 80% locked down by 1 p.m., but of course breaking news can always cause us to change the format, even when we're live

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