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Curr Mol Med 10:369373 Apte RN, Krelin Y, Song X, Dotan S, Recih E, Elkabets M, Carmi Y, Dvorkin T, White RM, Gayvoronsky L, Segal S, Voronov E (2006) Effects of micro-environment- and malignant cell-derived interleukin-1 in carcinogenesis, tumour invasiveness and tumour-host interactions

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When the Surgeon General's report highlighted the links between smoking tobacco, heart disease and cancer, the tide turned again in the 1960s and 1970s

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After reviewing the existing laboratory, animal and human evidence, the Working Group concluded that nicotine-based e-cigarettes contain known carcinogens, Nicotine-based e-cigarettes are likely to be carcinogenic to humans who use them, and E-cigarettes are likely to cause lung cancer and oral cancer