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With the exception of tricyclic antidepressants, the correlation between plasmatic levels and the clinical outcome is still not consensual [7]

If the combination of prevalence and cigarettes per day figures are to be believed, then Italian consumption in 1949 was about double the reported legal sales for that year.[ii] One possible explanation is over-reporting: there were still many Italians in 1949 who could not afford to smoke all the cigarettes they would have liked

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Additional Information How the FDA is regulating e-cigarettes (updated Sept