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The following information was extracted from each study: the first authors surname, publication year, location (country or region) of the conducted study, follow-up time, the total number of participants and cancer cases identified among them, age of the participants, smoking categorization used, relative risk (RR) or hazard ratio (HR) estimate for each smoking category, and the corresponding 95% confidence interval, and finally the confounder variable that was adjusted for in the analysis

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"It became a game for them," de Villiers says

Overall, it spends about $50 million less than what it needs to, he said

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