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19) Public Health England, Local Tobacco Control Profiles

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However, comparing these studies is challenging due to differences in study designs, populations, time intervals, definitions of smoking outcomes, and different regulations in each country for e-cigarette sales and import

It is worthy of note that tobacco snuff-induced hepatic damage is without doubt caused by its ability to generate free radicals, constitutive carcinogenic components, harmful heavy metals and 23 polycyclic aromatic hydrocarbons that are implicated in increased activity of serum hepatic parameters 6,7,30 and the progression of macrovesicular steatosis showed retrogression in the livers metabolic functions