Supplementing the studies in women, two recent studies
30 , 44 Acetaldehyde may also contribute to the addictiveness of tobacco by interacting with signalling processes in the brain that affect motivation, reward and stress-related responses
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Furthermore, if the patient also has concomitant substance use disorder(alcohol, opiates, other prescription medications) or is being treated for other chronic conditions or mental illnesses, a hospital or a rehab setting will be more beneficial in the withdrawal process as the possibility for complications is higher
