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Statements Data availability statement Raw data used for the study is provided in the Supplementary Material for download

[20] A 2015 PHE report found that high levels of formaldehyde only occurred in overheated "dry-puffing", and that "dry puffs are aversive and are avoided rather than inhaled", and "At normal settings, there was no or negligible formaldehyde release." [20] A 2018 study confirmed e-cigarettes can emit formaldehyde at high levels more than 5 times higher than what is reported for cigarette smoke) at moderate temperatures and under conditions that have been reported to be non-averse to users

R., Cantor, A., Alberts, W

Examples of increased risk factors for cannabis induced psychosis or schizophrenia include: heavy long-term cannabis use, a history of child abuse, a family history of psychotic disorders, or certain genetic predispositions: certain variants in the genes COMT and AKT1 are linked to a predisposition to psychotic disorders (10) PGx and the Future of Personalized Medicine Using PGx to guide cannabis usage for patients could provide a potential way of reducing the risk of negative symptoms

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