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1 2 AIDS Reviews 2005;7:67-83 Antiretroviral Drug Studies in Nonhuman Primates: a Valid Animal Model for Innovative Drug Efficacy and Pathogenesis Experiments Archived 17 December 2008 at the Wayback Machine 1 2 Nature

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Mechanisms such as oxidative stress, cytotoxicity, inflammation, mitochondrial dysfunction, and DNA damage have been documented in cell models and appear to be influenced by factors including liquid dosage, the chemical composition of flavorings, and the type of device used

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