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What the research says According to PubMed, a 2025 review of atrial fibrillation (Ko and colleagues, JAMA) reports that AFib substantially increases the risk of stroke, heart failure and death, that 1040% of people with AFib may be asymptomatic, and that for patients at meaningful risk, anticoagulation reduces stroke risk by roughly 6080% compared with placebo while aspirin is less effective and not recommended for stroke prevention in AFib

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Psychopharmacological interactions between nicotine and ethanol