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Physical side effects may include: Severe drowsiness Excessive fatigue that persists throughout the day, even with adequate sleep Dizziness and vertigo Balance problems that worsen when changing positions quickly Dry mouth Both substances reduce saliva production, compounding this uncomfortable effect Blurred vision Difficulty focusing or seeing clearly, particularly problematic for driving Cognitive and emotional effects often involve: Memory problems Short-term memory becomes more impaired than with either substance alone Increased anxiety Paradoxical anxiety spikes, especially with high-THC cannabis strains Mood swings Emotional instability as both substances affect different aspects of brain chemistry Concentration difficulties Reduced ability to focus on tasks or follow conversations Is It Safe to Mix Lexapro and Cannabis