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To best create these translatable pre-clinical animal models, it is necessary to standardize factors such as puff frequencies and topographies, exposure concentrations, e-liquid composition and device generation/brand

Menthol cigarettes are also said to be easier to inhale, which makes it easier for harmful chemicals to be absorbed in the body, and may also be more addictive than nonmenthol cigarettes

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The AHA also says that it is reasonable for physicians to support a patients use of an e-cigarette to stop smoking if they have failed approved therapies and would like to try this approach -- a far cry from doctors prescribing the devices to patients