Eating high-purine foods like red meat, organ meats, and certain seafood Alcohol consumption , especially beer and spirits, which increases serum urate levels Dehydration , which reduces kidney function and raises serum uric acid levels Taking medications such as diuretics or low-dose aspirin Living with chronic kidney disease , which limits urate excretion Having other chronic diseases like coronary heart disease or rheumatoid arthritis Cigarette smoking may increase systemic inflammation and affect uric acid metabolism High body mass index , which is linked to higher uric acid levels Genetic background or a family history of gout , as shown in statistical analysis from large health studies Some studies, including the Singapore Chinese Health Study and analyses from the Korea National Health and Nutrition Examination Survey, suggest a potential association between smoking and an increased risk of developing gout, particularly among current smokers

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